In Vivo Antiplasmodial Activity of Two Sahelian Plant Extracts on Plasmodium berghei ANKA Infected NMRI Mice
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منابع مشابه
In vivo Antiplasmodial and Cytotoxic Activity of Achyranthes aspera and Ficus thoningii in Mice Infected with Plasmodium berghei
Malaria remains o n e o f the leading causes of morbidity and mortality in tropical countries, and the alarming spread of the drugs resistant malaria parasite underscores the need to develop new antimalarial compounds. In this study, the phytochemical constituents, in vivo antiplasmodial, and cytotoxic activity of methanolic extracts of Achyranthes aspera and Ficus thoningii were evaluated usin...
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The objective of the present study was to investigate the antiplasmodial effect of the ethanolic stem bark extract of Anthocleista vogelii at different doses in albino mice infected with Plasmodium berghei berghei (NK 65). Thirty-six mice were divided into six groups of six mice each. Five groups (B1-B3, D, and G) were infected with Plasmodium berghei berghei parasitized red blood cells. Groups...
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The antiplasmodial activity of crude ethanol extract of Vernonia amygdalina leaf in Plasmodium berghei infected mice was evaluated. A total of 20 mice were randomly distributed into five groups of four mice each. The infected mice were treated immediately after inoculation with 200, 400 and 600mg/kgbw of the extract respectively. Group 4 (Positive control) was treated with standard drug (Chloro...
متن کاملAntiplasmodial activity of Ajuga bracteosa against Plasmodium berghei infected BALB/c mice.
BACKGROUND & OBJECTIVES The present work was undertaken to evaluate antiplasmodial activity of ethanolic leaves extract of traditional medicinal plant Ajuga bracteosa in Plasmodium berghei infected BALB/c mice along with its phytochemical screening and acute toxicity test to support its traditional use as a remedy for malaria. METHODS Plant extract (ethanolic) 250, 500, 750 mg/kg/day was eval...
متن کاملIn vivo antimalarial activity of crude extracts and solvent fractions of leaves of Strychnos mitis in Plasmodium berghei infected mice
BACKGROUND Malaria is a major public health problem in the world which is responsible for death of millions particularly in sub-Saharan Africa. Today, the control of malaria has become gradually more complex due to the spread of drug-resistant parasites. Medicinal plants are the unquestionable source of effective antimalarials. The present study aimed to evaluate antiplasmodial activity and acu...
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ژورنال
عنوان ژورنال: Evidence-Based Complementary and Alternative Medicine
سال: 2018
ISSN: 1741-427X,1741-4288
DOI: 10.1155/2018/6859632